BIOL 314 Lecture Notes - Oncogene, Tumor Suppressor Gene, Stomach Cancer
26 Nov 2013
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Biol 314 molecular biology of an oncogene. Classification of cancer: tumors arise from normal tissues: it is an abnormal cell growth in a normal tissue, tumors arise from one of the specialized cell types deriving from the 3 layers of the embryo . Cml has a survival rate of less than 10% in adults: glioblastoma is a very fatal form of cancer but now can be treated for if identified early. Signaling pathways have ben conducted: models of multistep process illustrate the links between cytogenetic changes and disease stage, tumors result from an initial monoclonal growth: genetic changes accumulate during tumor progression and make the kc more aggressive. Importance for prevention and treatment in most epithelial cancers (breast, colon, prostate etc. ) It"s constantly being altered and the mutations in turn are constantly being altered and cancers result because of different mutations. For example in the japanese example, prostrate cancer incidence has increased over time whereas stomach cancer has actually decreased.
