BIOC 311 Lecture Notes - Lecture 22: Cytosol, Carboxylic Acid, Glycogen

• School: McGill University
• Department: Biochemistry
• Course: BIOC 311
• Professor: Julie St- Pierre

Document Summary

Mammalian adipocytes: composed of tag, highly efficient storage cell. Plant seed: instead of having ld, they have smaller oil droplets, good portion of cell taken up by fat. Insulation, good for padding of vital organs (protect from acute damage) Lots of electrons in fat, try to strip electrons from fat and go through etc to produce atp. Fat is coated by perilipin, which form a nice barrier, and conserved the lipid droplets. If perilipin is phosphorylated, you will have the opening of barrier. Glycerol is delivered to liver (can convert it into dhap to be used in glycolysis or gluconeogenesis, or be phosphorylated (glycerol-p) and serve to make new fa. You need your ffa to be in mitochondria for breaking down them down by b-oxidation. Transport in liver: carnitine shuttle (from cytosol to mitochondria) Fatty acyl synthetase (thiokinase) is using atp and coa to convert fatty acid to fatty acyl.