BIOC 311 Lecture Notes - Lecture 23: Inositol, 3 Ft Gauge Rail Modelling, Methylation

• School: McGill University
• Department: Biochemistry
• Course: BIOC 311
• Professor: Julie St- Pierre

Document Summary

Lecture 23: lipids and lipoproteins vendredi 30 octobre 2015. Fatty acid: long chain of hydrocarbon with carboxyl group at position 1. 18:1(d9): oleic acid, one double bond at 9 position. 20:4(d5, 8, 11, 14): arachidonic acid, poly-saturated fa (spacing of 3 between double bonds) (precursor to icosonoids) A cis double bond introduces a kink in fatty acid. A trans double bond does not introduce a kink in fa. However, we do not make trans fatty acid (chemists do). Different products found in nature have different proportion of fatty acids. => changing types of fatty acids, you change the properties of product. Look at fatty acid composition of e. coli cells cultured at different temperatures. 40c: lots of palmitate (saturated) and not much of the other ones. 20c: amount of palmitate goes way down (half), amount of unsaturated fa it increases. There is a reciprocal balance between different temperatures cultures and the introduction of unsaturated fa.