EDKP 395 Lecture Notes - Lecture 8: Autoregulation, Arteriole, Succinate Dehydrogenase

• School: McGill University
• Department: Kinesiology&Physical Education
• Course: EDKP 395
• Professor: Russell T Hepple

Document Summary

Skeletal muscle vasodilation (arterioles: autoregulation via sns. Bf increased to meet metabolic demands of tissue i. e. rvasodilation regulated by metabolic need of muscel. Nitric oxide synthase: promotes smooth muscle relaxation. Vasoconstriction to visceral organs and inactive tissues: via sns regulated by cardiovascular control center. O2 delivery to exercising muscle increased due to: increased co. As a linear function of o2 uptake during exerise. Sv reaches a pleateau at ~40-60% vo2max. After that increases in co are due to hr alone: redistribution of bf from inactive organs to contracting skeletal muscle. Depend on: type, intensity, duration of exercise. Hr/bp arm >> leg: environmental condition. Onset of exercise: rapid inc. in hr, sv, co, plateau of sv during sub-maximal (below lactate threshold) & steady state exercise @ 40% vo2max. Co continues to inc. due to hr. During recovery: decrease hr, sv, co towards resting levels. Slower/longer than rapid increase at onset of exercise: depends on.