EDKP 395 Lecture Notes - Lecture 21: Lactic Acid, Acidosis, Chemoreceptor

• School: McGill University
• Department: Kinesiology and Physical Ed
• Course: EDKP 395
• Professor: Dennis Jensen

Document Summary

1- increased exercise intensity = pyruvate production more than can be. 2- excess pyruvate ldh lactic acid [la+] + [h+] 3- respiratory control center signal to alveolar ventilation va to breath more. *use respiratory muscle disproportionally more than metabolic demand. 4- increased alveolar ventilation va = expire more co2. = paco2 & paco2 because expiring more co2: lower paco2 = restrain magnitude of rise in [h+] *prevent [h+] & acidosis. *excess co2 = more [h+] & less co2 -= less [h+: lower paco2 = increase pao2 alveolar oxygen *facilitate o2 gas exchange & saturation of blood. Vco2/vo2 = pao2 because inspiring more co2. *heavy exercise lactate & hydrogen = stimulate chemoreceptors = send to control center. Stimulate ventilation more alveolar vent than metabolic rate of co2 produced/metabolic demand. Regulation of arterial blood [h+] during progressive exercise. 1- minute ventilation ve increase with increase in arterial [h+] *dose response. *as blood more acidic = ventilation more stimulated.