EDKP 485 Lecture Notes - Lecture 17: Ejection Fraction, Team Ldlc.Com, High-Level Data Link Control

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Adaptations of exercise = either peripheral muscles or central cardiac myocardium. Peripheral adaptations to cardiac rehab in coronary artery disease. 1- peripheral adaptations to cardiac rehab in cad. Study = 60 older cad patients 41 men *most affected + 19 women] Treadmill = 25 min/session + stationary cycling = 15 min/session & Rowing ergometer = 10 min/session at high 75-90% of hrmax 3x /wk. Results= compared to age-matched sede(cid:374)tary (cid:858)usual care [ eco(cid:373)(cid:373)e(cid:374)datio(cid:374)s](cid:859) control group (n=10) Work load but no in resting hr no change in peak hr/resting ef/peak. *peak exercise ejection fraction = blood/beat relative to amount of blood before blood. Since peak vo2 increased but no in peak co = then must be c(a-v)do2 increased. *flux to oxidative phospho= depend on o2 substrate & # number or activity of mitochondrial enzyme. Conclusion = no central cardiac improvement but peripheral improvement since peak vo2. Even if cad have cardiac impairment = peripheral muscles adapt & more fit.

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