EDKP 485 Lecture Notes - Lecture 10: Chronic Obstructive Pulmonary Disease, Shortness Of Breath, Myopathy

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Effects of copd on the peripheral locomotor muscles: disuse or dysfunction . What is the consequence of this disease on peripheral muscles! Caused by myopathy: no known answer, but there are researcher biases, this will be angled towards jensen"s bias which is more on the belief that chronic disuse leads to exercise intolerance. Decline of resting inspiratory capacity (ic) in copd: impact on breathing pattern and exertional dyspnea. Lung hyperinflation predicts how quickly a patient with copd reaches mechanical limitation at low levels of exercise, compared to those with lesser hyperinflation: lung volume at rest dictates room to breathe during exercise. With an earlier onset of mechanical limitation means a faster rate of symptom progression. Inability to expand lung volume is same across all classes of the disease: but where you are breathing along p/v curve for a certain ventilation is dictated by the disease severity. The mechanical constraints that exist dictate how quickly someone becomes breathless.

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