EDKP 495 Lecture Notes - Lecture 4: Bed Rest, Myocyte, Citric Acid

• School: McGill University
• Department: Kinesiology and Physical Ed
• Course: EDKP 495
• Professor: William James Harvey

Document Summary

Detraining / bed rest & effects on what we know about microgravity. Training = stress so body adapt with physiological changes new level of homeostasis. Results = decrease vo2max due to decrease in cardiac output & stroke volume + oxidative enzyme. Time course of changes in human skeletal muscle succinate dehydrogenase & cytochrome oxidase. Results = changes at local muscle & systemic level in maximal capacity to utilize oxygen. Adaptive changes in work capacity, skeletal muscle capillarization & enzyme levels during training & Results = showed that decrease in vo2max although some adaptation but capillarization remains. *benefit of retraining because of remnant residual effect = can adapt quickly with training after. Time course of loss of adaptation after stopping prolonged intense endurance training coyle et al. End-point of highly trained will be lower than baseline. *some increase in vo2max due to compensation but generally declining. = if too low can lose ability of daily living.