LSCI 204 Lecture Notes - Lecture 17: Polynucleotide, N-Formylmethionine, Polynucleotide Phosphorylase

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Bowen conradi syndrome results from defective ribosome biosynthesis, affecting the process of translation. The genetic code determines how the nucleotide sequence specifies the amino acid. The amino acids in proteins are joined together by peptide bonds to form polypeptide chains. A protein consists of one or more polypeptide chains. Polypeptides have polarity, with one end having a free amino group (nh3+) and the other end possessing a free carboxyl group (coo ) The primary structure of a protein is its sequence of amino acids. Interactions between amino acids cause the primary structure to fold into a secondary structure, such as this alpha helix. The secondary structure folds further into a tertiary structure. Two or more polypeptide chains may associate to create a quaternary structure. (a) primary structure (b) secondary structure (c) tertiary structure (d) quaternary structure. The genetic code consists of 64 codons. The amino acids specified by each codon are given in their three-letter abbreviation.

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