LSCI 204 Lecture Notes - Lecture 12: Heredity, Lysis, Reverse Transcriptase

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Chapter 8: dna: the chemical nature of the gene. Genetic material must: contain complex information, replicate faithfully, encode the phenotype, have the capacity to vary. All genetic information is encoded in the structure of dna or rna. Dna as the source of genetic information. Table 8. 1 base composition (percent*) of dna from different sources and ratios of bases. When griffith injected type iir (nonvirulent) bacteria into mice, the mice lived: no bacteria were recovered from their blood. When he injected large amounts of heat-killed type. Iiis bacteria into mice, the mice lived: no type iiis bacteria were recovered from their blood. Griffith concluded that the type iir bacteria had somehow been transformed, acquiring the genetic virulence of the dead type iiis bacteria. Enzymes such as trypsin and chymotrypsin, known to break down proteins: had no effect on the transforming substance. Ribonuclease, an enzyme that destroys rna: also had no effect.

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