NSCI 200 Lecture Notes - Lecture 4: Voltage Clamp, Pronase, Resting Potential
15 Jul 2016
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Ion transporters set up the initial ionic gradient across the cell membrane; Inside cell: high k+, low na+, low cl- Outside cell: low k+, high na+, high cl- Inside the cell, charge is mostly neutral because of a variety of impermient anions(-) present. As cl enters the cell, it hyperpolarises the cell membrane, na+ depolarize when entering, k+ leaving cell hyperpolarizes. electrostatic force pulls k+ back inside the. :it describes the force produced by each ion"s gradient, in mv (electrical) : gives the resting membrane potential when the 3 ions reach electrochemical equilibrium. Driving force: is higher if the difference btwn the membrane potential and the ions equilibrium potential is big. at resting potential na has a higher driving force then cl- (approx. When glutamate receptors cause an opening of both k+ and na+ channels, it causes depolarization because ek and.
