NUTR 344 Lecture Notes - Lecture 4: Blood Sugar, Skeletal Muscle, Adipocyte
9 Aug 2019
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Review: % of energy expenditure at rest, skeletal muscle 22, liver 21, enzymatic reaction, brain 20, heart 9, kidneys 8, adipose tissue 4, remainder 16, fuels in a 75kg man. Lecture content: blood glucose and the fed state, adaptation to fasting, protein sparing, ketogenic diets, re-feeding syndrome, weight regain. Readings: nelms:chap 17 pp. 474-479, cahill, sumithran & proietto kcal. Lost of rapid weight loss lost of glycogen/protein associated water lost. Insulin, glucose, lactate, pyruvate, tgs (diet derived), alanine, bcaa, total aas (diet), i:g: initial decrease, glucagon, ffa (elevated in the fasted state from glycolysis), ketone bodies, glycerol, Insulin and glucagon mainly: decrease i in muscle higher catabolism, decrease i and increase g in liver increase production of glucose, gh and catecholamines (en, no) Ideally nh4 excreted because it is a waste product: but k preferred ion to be excreted hypokalemia, substrate and hormone levels donotknow numbers know the pattern.
