PHAR 300 Lecture 14: PHAR 300 - lecture 14

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Ebers papyrus, 1550 bc medicated tampon to prevent pregnancy. There are some parts of the world that use very little contraception (8%) and others that use much more (72% in canada) Pearl index effectiveness of contraception based on pregnancy rate 1 year after exposure (out of 100 women) None = 85%, spermicide = 26%, periodic abstinence = 25% Best ones are condom, vaginal ring, ocp, iud and sterilization. Usa ocp, iud, male condom, female/male sterilization. France no use of sterilization but the pill is widely used instead. Oocyte is ovulated released from ovary into fallopian tube transferred to uterus fertilized by sperm and implanted into endometrium. Once implanted, it will start to grow and develop. All events are timed and regulated by hormones. They regulate fertility can increase or decrease it. Cancer chemotherapy hormones play a role in certain types of cancer. The cells have receptors for the sex hormones so hormone manipulation can be used for therapy.

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