PHAR 300 Lecture Notes - Lecture 8: Weak Base, Basal Metabolic Rate, Cholinergic

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Addiction: vaping: a variation on smoking, dopamine pathways: ventral tegmental area projects to the nucleus accumbens and the frontal cortex. Neurons are talking to each other all the time. There are so many ways that drugs can act on. Involved in reward and memory, but also in addiction. neurons. Nicotine: the inherent insecticide present in the tobacco plant. It has been isolated for years and used as insecticide. It is no longer favoured as an insecticide because it is too toxic. The tobacco plant would be dead without the nicotine: 2 variations on the smoke: Mainstream smoke: what the smoker sucks in and blows out. Side stream smoke: what comes out the burning section of the cigarette. Other people in the room are mostly exposed to side stream smoke. Smoking: a cigarette acts as a drug delivery system, the nicotine first goes into the lungs, is absorbed into the bloodstream and pumped to the rest of the body.

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