PHGY 209 Lecture Notes - Lecture 11: Cowpox, Innate Immune System, Smallpox
14 Nov 2016
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In autopsy, found no thymus gland in neck, no 3rd and 4th pharyngeal pouches, no lymph nodes. So we know, these three things are involved in immune system. Another crucial factor for immunity is the t4 helper. Form in uterus before birth (stem cells from the yolk sac and the fetal liver)******exam. In fetus, stem cells go from yolk sac to fetal. Secondary organs (also form in utero; before birth!) Dr. edward jenner: saw that milkmaid were immune to small pox. He inserted pus from cow pox into people. Hapten (+ carrier = immunogen) (has to be carried in order to trigger an immune response; hapten itself is super small) Tolerogen (e. g. when you receive a kidney transplant, chances are high that your body will reject it. Yet, our bodies are tolerant to our own that your body will reject it. Yet, our bodies are tolerant to our own organs. ) Skin & mucous membranes have unpleasant living conditions for microorganisms.
