PHGY 209 Lecture Notes - Lecture 17: Creatinine, Toxin, Alpha-Amylase
Document Summary
3-removal of foreign chemicals (antibiotic) from blood & their. 4-production of hormones/enzymes (endocrine function: erythropoietin hormone that controls erythrocyte production (rbc in bone marrow- anemic, renin. Enzyme that controls formation of angiotensin & influences blood pressure & Active vit d that influences calcium balance/bone health (activation require. Kidneys [renal] = paired (2) organs- ~150g each. Behind peritoneum on either side of vertebral column against posterior abdominal wall (lower back) 2 kidneys connected to bladder through 2 ureters. Nephron - each kidney = ~1 million nephrons (subunits) 4- afferent arteriole = from interlobular to nephron. Cortex - renal corpuscle -> glomerus & bowman"s space. Start at cortex / end at medulla -> proximal convoluted & straight. Descending limb + ascending/thick ascending limb (with macula densa) = medulla -> go (cid:271)a(cid:272)k to bo(cid:449)(cid:373)a(cid:374)"s capsule. Nephrons merging: cortical collecting= cortex, medullary collecting = medulla. Vis(cid:272)e(cid:396)al laye(cid:396) of bo(cid:449)(cid:373)a(cid:374)"s capsule = podocytes -> barrier for bo(cid:449)(cid:373)a(cid:374)"s pa(cid:272)e/u(cid:396)i(cid:374)e - capillary/blood.
