PHGY 209 Lecture Notes - Lecture 6: Diaphysis, Enzyme, Globin
14 Oct 2017
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Document Summary
The osmotic pressure of a solution depends on the number (not their configuration, size or charge) of osmotically active particles/unit volume. Each protein fraction exerts an osmotic pressure which is: (i) directly related to its concentration in the plasma (ii) inversely related to the molecular weight of that protein. Weight, the less particles thus less osmotic pressure. **albumin (~20mm hg) >>> globulins (~5mm hg) >> fibrinogen (<1mm hg) Factors in transcapillary dynamics: hydrostatic pressure (filtration, c. o. p. (plasma proteins, capillary permeability (relatively protein impermeable; under certain conditions proteins may escape, lymphatic drainage. Edema accumulation of excess fluid in the interstitial spaces. Under which conditions can edema develop: hydrostatic pressure, plasma protein (i. e. c. o. p. , capillary permeability, obstruction of lymphatic drainage. Failure to synthesize plasma proteins (ex: liver disease) Normally, there is very little protein in isf. If the capillary wall becomes more permeable, some plasma proteins escaped into the isf where they can exert an oncotic effect.
