PHGY 209 Lecture Notes - Lecture 3: Body Water, Electrolyte, Perspiration

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Fundamental principle: all levels of organization, functional activities are directed at maintaining homeostasis relative constancy of the milieu interieur (internal environment) Milieu interior: environment surrounding individual cells is vastly different from external environment, internal environment remains relatively constant under conditions of health, comprises of the various body fluids. Body fluids: aspects: volume, distribution, characteristics, function (very interested, water - most abundant single constituent (45-75% large variety in % water) Is the solution where solutes are all dissolved & metabolic rxns take place. Body water as % of body mass. Absolute amount water equation (weight(kg)x percent water)/100 = kg = l. 0. 0024mg/ml: body water remains constant in health dynamic steady state , obligatory losses: mandatory 1. 5l of water/day. 0. 5l urine + stool: facultative losses: vary with intake urine (kidney is major homeostatic organ) Normally individual is in water balance body water volume should be constant: adult 24hr turnover 3-4%

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