PHGY 209 Lecture Notes - Lecture 24: Neutrophil, Natural Killer Cell, Immunoglobulin E
21 Jul 2016
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2 identical light chains and 2 dark chains immunoglobulin molecules o 5 claseses0 determined by heavy chain delta mu gamma alpha and epsilon. o 2 types determined by light kappa and lambda o each chain has 2 identical h and l o interchain and intrachain disulfide bonds are present between and within all chains o fragments prepared by lab cleavage result inp. There are two groups: o myeloid include neutrophils, basophils, eosinophils, and monocytes o lymphoid includes b cells, t cells, natural killer cells, and plasma cells which differentiate from b cells during immune responses: the major function of plasma cells are to synthesize and secrete antibodies, macrophages found virtually in all organs and tissue and derived from monocytes that pass through the walls of the blood vessels to enter the tissues and transform into macrophages, dendritic cells cell populations that are not macrophages but exert certain macrophage like functions.
