PHGY 209 Lecture Notes - Lecture 8: Yolk Sac, Cd28, Thymus
16 Sep 2016
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Humoral (immunoglobulin/antibody mediated) o immunoglobulin/antibodies are soluble in serum o for bacteria. Limbs of the immune response (humoral and cellular adaptive immunity) o. Afferent limb" is made up of the events that initiate the immune response. Innate immunity to the interaction with the t helper (th) cd4+ lymphocyte. This limb will have both humoral and cellular components in both the humoral and cellular immune. Response mechanisms o efferent limb" is the effector, or killing", aspect of immunity. In the humoral immune response, this is antibody molecules (that will engage the complement. In the cellular immune response, this will be t cytotoxic cells (tc) cd8+ lymphocytes. Every molecule in the body has an mhc (major. The major histocompatibility complex: mouse: h2 complex. Hla-dr) o each have multiple alleles o in each class, molecules have 2 chains alpha and beta. In mhc (hla) class i molecules, the chains are of markedly different molecular masses: a large alpha chain, and a small beta-
