PHGY 209 Lecture Notes - Lecture 99: Calmodulin, Anatomical Terms Of Location, Classical Conditioning
Document Summary
Hiv/aids = genetically transmitted -> missing particular cell (cd4+t-cell) can"t initiate immunity. Secondary #2 organs where cells go after bone. Vaccination - small pox= dreadful infectious disease 1/10 dead people for centuries. Edward jenner noticed milkmaids immune because already infected by cowpox from milking cows - *cross-relative phenomenon - last case of small pox in wild 1977- ali maalin/lab 1978 1 deaths (2 cases) Cannot rise to immune response without carrier (+ carrier = immunogen) Rise to allergic reactions & requires particular antibodies. Only recognize/tolerate own body -> rejects others (start in uterus) Skin & mucus membrane = unpleasant living conditions for micro-organisms. Cellular & humoral immunity (dissolved in fluids - * no memory -> will react the same way every time (best protection needs memory) Response: first #1 cell involved in innate response once bacteria enter skin= fixed tissue macrophage. * tlr bind to pamp to find out pattern & tell different tlr to come get involve.
