PHGY 210 Lecture Notes - Renal Blood Flow, Renal Pelvis, Afferent Arterioles

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150 g population is born with only 1 kidney but live normal lives. After blood flows around, it is collected back in the venous system & backtracks the way it came. Each kidney contains ~1 million subunits called nephrons. No proteins in the bowman space fluid = no oncotic pressure: power to pull water back in is because of the [proteins] Figure 14. 08forces involved in filtration(oncoticpressure)glomerular capillary wall(filtration barrier)visceral glomerular epithelial cells (podocytes)gbmendothelial cells. Gfr: the volume of fluid filtered from the glomeruli into bowman"s space per unit time. Normal gfr for a 70kg person is 180l/day. Normal plasma volume is ~3. 5l plasma is filtered 51 times per day at glomeruli. Filtered load: the total amount of any freely filtered substance. Net filtration pressure: only physiologically-significant method, decreased gfr. Measure of kidney failure: increased gfr. Membrane permeability and surface area available for filtration: only relevant in pathological conditions.

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