PHGY 312 Lecture Notes - Lecture 6: Central Pattern Generator, Pulmonary Stretch Receptors, Hypoventilation
24 May 2016
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Phgy 312-lect6: breathing pattern (choosing how to breathe) 3 types of neurons: inspiratory, expiratory, and post-inspiratory. In-phase, out of phase with the phrenic (innervates the diaphragm) Neurons interact in a network; in isolation, does not work. Pattern generated get transmitted to motor neurons through spinal pathway. Pathway connecting resp muscles to motor neurons (posterior and lateral) Posterior = inspiratory/ expiratory, voluntary in lateral areas. If person has bilateral lesion of voluntary pathways, patient cannot control breathing patterns. If person has bilateral lesion of involuntary pathways = central hypoventilation = patient must think to breathe! Respiratory neuro mech unit: o o o o o o o o. Activation of respiratory muscles muscle (force) pressure (p = f x area) external power (p x ventilation) Central pattern generator ventilation relative to metabolic rate, you have chemo receptors (+), chest wall proprioceptors (-), and airway stretch receptors (-) that feed back to the central pattern generator.
