PHGY 312 Lecture Notes - Lecture 3: Pressure Measurement, Chronic Obstructive Pulmonary Disease, Vital Capacity

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Penumotachography = pressure difference in tube is proportional to flow. If you integrate flow over time, you get a spirogram (shows tidal volume)-flow vs volume. Don"t know absolute lung volume during spirography just relative volumes during maneuvers. When subject breathes in, pressure goes up because the gas around the subject is being compressed o. Pafrc = pa (frc-deltav), from here, we know pa so we calculated frc. Helium dilution o o o o blood) o. Helium equilibrates into the lung; helium has low solubility (will not pass into. Tumours: he doesn"t reach airways; value lower than what you get through body pletsmograph o. Ppl = pesophageal = placed through nostrils until it reaches esophagus = -5cm. But when inflated more and more, compliance decreases! Chronic bronchitis = emphysema = floppy balloon = inflate lung more easily = increased compliance o o. Copd= max volume is increased (chronic obstructive pulmonary disease)

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