PSYC 337 Lecture Notes - Lecture 4: Differential Diagnosis, Hypersomnia, Libido
Document Summary
Good rat mothering (licking, nursing) leads to better neural function in offspring. Bad mothering leads to high stress level in the presence of common stressors. Pubs showed change in cortisol functioning and epigenetic effect (glucocorticoid receptor gene) Also due to the way we measure things, imprecise and overlap a lot, the phenotypes are too heterogeneous, comorbid to be linked to certain genetic effect. Must not be state dependent e. g. vulnerability marker, should predate the illness. Must be higher rate in affected families than general population. Manic depression: bp & mdd, primary mood disturbance. Dementia praecox: cognitive disintegration: attention, memory, goal-directed behavior later labelled as schizophrenia. Bp is very rare to have manic only, will eventually develop depression and becomes bp. In dsm 5 bp is between depressive and schizophrenia , in terms of symptoms similarity and genetics, family history. Bipolar: diagnosis based on presence of manic episode. Flight of ideas and distracting thoughts, appear similar to schizophrenia.