PSYC 427 Lecture Notes - Lecture 19: Deep Cerebellar Nuclei, Basal Ganglia, Striatum
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Exam info: general questions looking for specific answers. Both basal ganglia and cerebellum receive input from cortex and output information back to cortex that is, they form multisynaptic loops with cortex that influence cortical motor areas. Imaging studies show that parkinson"s patients have increased cerebellar activity that is normalized with deep brain stimulation of the basal ganglia. This suggests that basal ganglia and cerebellum might be connected. Cerebellar patients increased activity in cerebellar cortex. When you have deep brain stimulation, eliminate parkinson"s symptoms and excessive cerebellar activity. So maybe basal ganglia and cerebellum are anatomically connected! Loop like arrangement exists between cerebellum and bg. Rabies virus was injected into different locations within the basal ganglia: (a) putamen, (b,c) external segment of the globus pallidus (gpe) Injection labels order neurons in contralateral deep cerebellar nuclei. First order neurons are in the striatum, second order neurons are in thalamus, third order neurons are in cerebellar output nuclei. in gpe third.
