ANTHROP 3PP3 Lecture 4: Lecture 4
Document Summary
Congenital doesn"t equal genetic (usually but not always) Can be hereditary or acquired between fertilization and birth. In britain, pregnant women are tested for syphilis. Multifactorial disorders (58. 4%) combo of different genetic disorders or genetics + environment. Any disrupting factor during early fetal development. Maternal rubella (german measles) cleft palate, spina bifida, down"s syndrome, microcephaly: mumps, chicken pox, shingles (herpes zoster) Congenital disease can rarely be ascribed to a single cause. True rate of congenital disease unknown due to spontaneous abortions disorder is incompatible with life. Infant died due to other factors (before congenital disorder was expressed) Problem process of endochondral bone formation. Cranial vault, face, and clavicles are normal". Earliest skeletal evidence from late upper paleolithic (10,000 bp) in italy. Example: seneb w. wife and children (4th/5th dynasty) scribe. Not just skeletal evidence, but also representations in art and carving. Infants do not survive long after birth. Basic defect: lack of development of the skull vault.