BIOCHEM 2EE3 Lecture Notes - Lecture 7: Adenylyl Cyclase, Phosphorylase, Glycogen Phosphorylase
7 Mar 2018
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Document Summary
Signal transduction the process in which the body communicates extracellular messages via long distances from remote locations (hormones) or locally over short distances (neurotransmitters) to elicit a speci c reaction within the targeted cell/tissue. Classes of extracellular messengers/signals hormones neurotransmitters pheromones - secreted from one organism an exert e ect on another organism growth factors. Types of hormones peptides (insulin, glucagon) steroids (vitamin d, estrogen) amino acid derivatives (epinephrine, thyroxine) It travels through the bloodstream and subsequently binds to the glucagon receptor on liver cells to elicit the cellular response which is the release of glucose from its glycogen stores. Transduction in the case of epinephrine binding to beta adrenergic receptor, the transducer is a g protein. Cell response active g protein interacts with an actives "e ector" which is an enzyme called ac. At synthesis to support muscle contraction this is reason epinephrine was released initially - due to muscle contraction initiated.
