BIOLOGY 1A03 Lecture 7: Theme 3 Module 3 and 4 Applied Lecture

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Lovaye Kajiura

Document Summary

What your mom ate (vitamins) influence specifically your gene expression during development. Folic acid - high amount of methyl groups. Proper methylation of your histone tails and promoters to turn genes on and off when you need them or when you don"t need them. Found in people with many diseases - diabetes etc. Cancer cells - have very different genetic profile compared to normal cells. Gene that controls how much you grow as a cancer cell - you can grow more rapidly. Can decrease expression of genes that are needed to keep cell growth in check or repair dna, initiate programmed cell death etc. The agouti gene: signals melanocytes to switch from producing black to yellow pigment. These two mice are genetically identical: monozygotic twins. The difference in them is because of the agouti gene. The difference in them is because of the agouti gene (gene expression differs) Chunky mouse - diabetes - because of agouti gene.