BIOLOGY 1A03 Lecture Notes - Lecture 20: Zygosity, Sickle-Cell Disease, Stop Codon
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BIOLOGY 1A03 Full Course Notes
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155 000 000 base pairs with approximately 1100 genes. Colour-blindness can"t distinguish between red and green. Hemophilia clotting factors, fibrinogens aren"t working well. Meiosis i allows for variation in gametes. Variation can occur in crossing over events within non-sister chromatids between homologous chromosomes. Trend with two loci associated with chromosome. Short chromosome can"t make as many crossing over events compared to a longer chromosome. Use pedigree analyses with association in the x chromosome. Carriers are phenotypically normal but genotypically have the gene that results in the disorder. Use genetic markers and their associations with genes. Looking for association or non-association with gene. No strong association with marker and gene. *marker b is no association with equal chances. Chance of recombination of marker a in mutant gene relatively rare. Large number recombination is relatively rare since they are close distance apart they are linked. Larger number of individuals find markers associated with snps.