BIOLOGY 1A03 Lecture Notes - Lecture 3: Embryonic Stem Cell, Cellular Differentiation, Gene Expression

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Dr.Da Silva

Document Summary

6: even though they have the same genome, gene regulation differences will lead to altered proteomes, which contribute to distinct differences in cellular functions. Chromatin remodeling: dna compaction regulates gene expression, transcriptional regulation is similar in prokaryotes and eukaryotes. Also, dna is organized into highly compacted chromatin. Dna compaction regulates gene expression: while compacting of dna into tightly wound chromatin fibers makes for an easy way to fit all the. Dna within the nucleus and also allowed for dna to be moved around during cell division, the winding of dna in nucleosomes can affect whether dna is transcribed or not. 10: genes within this tightly wound heterochromatin are usually not expressed, to be able to transcribe a specific gene product, it is necessary to unwind the dna. Within eukaryotic dna, we find that dna is tightly wound around a complex of histone proteins, o forming the nucleosome structure.