BIOLOGY 1A03 Lecture Notes - Lecture 31: Sense Strand, Spindle Checkpoint, Meiosis

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Kim Dej

Document Summary

Theme 1 the structure of the cell. Dna the hereditary material (griffith"s expt, avery et al, expt. ) Have information in our blueprint, code for important blueprints, along the way there are different proteins, transcription factors, many macromolecules playing a role in the cell. Be able to use the genetic code if you are given it: Beadle and tatum knew that each step in this metabolic pathway was catalyzed by a different enzyme. Beadle and tatum were able to exactly correlate a specific mutation with a specific defect in the biochemical pathway that synthesized arginine. Override do not need enzyme 2 if you give the cells citrulline or arginine. Lac operon is never fully off, always on even in high glucose environments at low levels. Transcription machinery the dna in eukaryotes (core and regulatory) can be connected by a regulator that forms a loop. Turning off expression (rna stability, protein stability: treating lactose intolerance, epigenetics and gene regulation (agouti mouse model)