BIOLOGY 2B03 Lecture Notes - Lecture 11: Centroacinar Cell, Invertase, Fructose
Document Summary
Phase constant microscopy allows us to see all the membranes of the cell with detail but immunofluorescence allows us to visualize the specific membranes of interest. Rough appearance due to the bound ribosomes. Site of co-translational transport, protein modification, and the vesicle formation that transports proteins from the er to the golgi. Site of carbohydrate metabolism and calcium sequestration to control calcium concentration in cytosol. Definition: addition of a polysaccharide or sugar group to a protein. Common for proteins that are secreted from the cell and proteins embedded in the cell membrane. **it is needed for proteins that mediate cell interactions with the extracellular matrix and for receptor-ligand interaction** It is the addition of the polysaccharide group to the nh2 of the r-group of. A protein modified in this way will remain on the luminal (exoplasmic) side of the er membrane during transport and so will be visible on the exterior surface of the protein embedded in the er membrane.
