BIOLOGY 2B03 Lecture Notes - Lecture 2: Reaction Rate, Scaffold Protein, Arginine
28 Mar 2018
School
Department
Course
Professor
Document Summary
Binding affinity: binding affinity is represented by keq (equilibrium constant, molecules cycle between the ligand, protein and ligand-protein complex, a high keq = reaction tends to the right where the protein is bound to the ligand. Indicates high affinity interaction in which the protein and ligand tend to stay together: a low keq = reactions tends to stay to the left. Indicates a low affinity interaction in which the protein and ligand readily fall apart. Catalysis speeds up a reaction: enzymes increase the rate of a reaction by lowering the energy of activation, when the enzyme recognizes the two substrates it brings them close together, facilitating the. If a reaction occurs to slowly it may be lethal to the cell reaction. It will take a higher concentration of low affinity substrate to get to vmax since the substrate and enzyme are more frequently dissociating: vmax is unchangeable at a fixed enzyme concentration.
