BIOLOGY 2B03 Lecture Notes - Lecture 8: Selectin, Commensalism, Exponential Growth
7 Apr 2018
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Document Summary
Module 8 in-class lecture importance of bacterial adhesion in infectious diseases. Methods for targeting adhesion to combat infectious bacteria. Infectious bacteria often use adhesion as the first step. Through respiratory system, g. i. tract, urinary tract. Source of e. coli is from colon itself. Upec wants to first adhere quickly and strongly since it"s in contact with the urinary system and there"s tons of fluids in there. Attachment: e. coli adheres to bladder cells, through pilli. Invasion: e. coli have signaling molecules that throw a kinase cascade that tells the human skeleton to engulf the e. coli so that a kinase changes and allows the thing to go into the membrane, which is nutrient rich. Replication: exponential growth until they take up volume of cecll, human cells sometimes respond to process called exfol. E. coli infection starts off with weak few attachment points. This is necessary step for next few steps to occur. It"s a protein that"s capable of binding to sugars.
