BIOLOGY 2D03 Lecture Notes - Fibrocartilage, Ossification, Osteocyte

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28 Jan 2013
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CONNECTIVE TISSUES, CARTILAGE, AND BONE
Functions:
mechanical support
defense (phagocytic cells roam conn. tissue)
communication (substrate for blood vessels, nerves)
ECM matrix determines CT type:
Basal Lamina
Loose CT
Dense CT (tendons, ligaments)
Elastic CT (skin, blood vess.)
Cartilage
Bone
RESIDENT CELLS:
from Primitive Mesencymal Cell (pluripotent)
FIBROBLASTS
lay down collagen in direction of migration
lay down other components of ECM
proliferate after tissue damage
WHITE FAT CELLS
store lipids as energy reserve
secrete regulatory molecules; production controlled by hormones
BROWN FAT CELLS
rich in mitochondria
heat-generative (short-circuits the electrochem. gradient energy
dissipates as heat)
MAST CELLS
histamine secretion in response to allergen binding
IMMIGRANT CELLS – see blood lecture
from hematopoietic stem cell
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