BIOLOGY 2D03 Lecture Notes - Lecture 3: Direct Fluorescent Antibody, Petroleum Jelly, Tacrolimus
o Direct fluorescent antibody staining of vesicular fluid
o Viral PCR
o Viral cultures.
Management
In some cases it can be difficult to determine if the eczema has been infected by bacteria
or viruses and both need to be treated.
MDT: If there is any concern about possible eye involvement, an urgent ophthalmic
opinion should be sought.
Conservative
Monitor hydration status and fluid intake
Cool wet presses
Petroleum jelly
Medical
IV acyclovir
IV antibiotics e.g co-amoxiclav
Analgesics
Antipyretics
Antihistamines, should be pre- scribed.
Steroids and other immunosuppressants (e.g. tacrolimus) should be
discontinued (this is in contrast to bacterial infections alone when steroid
creams are usually continued alongside the antibiotic). Topical treatments can
usually be restarted after 1 week when the patient has improved.
JWH, JM, AJS
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Document Summary
Jwh, jm, ajs: direct fluorescent antibody staining of vesicular fluid, viral pcr, viral cultures. In some cases it can be difficult to determine if the eczema has been infected by bacteria or viruses and both need to be treated. Mdt: if there is any concern about possible eye involvement, an urgent ophthalmic opinion should be sought. Steroids and other immunosuppressants (e. g. tacrolimus) should be discontinued (this is in contrast to bacterial infections alone when steroid creams are usually continued alongside the antibiotic). Topical treatments can usually be restarted after 1 week when the patient has improved. Ftt: (cid:272)hild"s weight drops a(cid:272)ross two (cid:272)e(cid:374)tiles/ is likely if weight below 2nd centile. Pc: ftt initially on the 25th centile now below 2nd centile , when she was weighed by the health visitor two days ago, feeding: Initially breast fed for first two weeks (encouraged by midwifery team)