BIOLOGY 3P03 Lecture Notes - Lecture 2: Electrical Network, Lipid Bilayer, Net Force
20 Sep 2017
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Bio3p03: membrane potential: ionic equilibrium i (lecture 2) If one of the two ions is extremely slow, making it essentially impermeable; Nernst equation: at equilibrium, the equilibrium potential is given by the nernst equation, eion = rt/nf ln [ion]out/[ion]in. Eion = equilibrium potential for the ion. T = absolute temperature k (273 + ) F = faraday"s constant (which is the charge carried by one mole of univalent ion) = 96 500 coulombs. Eion = 58/n log [ion]out/[ion]in: note: the nernst equation applies only to one ion at a time and only to ions that can cross the barrier. Amount of charge transferred (i. e. the number of cl- ions) is extremely small. Charge separation summary: all bioelectric potentials result from separation of charge across membrane, amounts of charge separated are too small to in uence concentration in bulk solution, (based on the previous example) e. g. Ecl = (58/-1) log [1/0. 1] = -58 mv.
