BIOLOGY 4X03 Lecture Notes - Lecture 4: Basal Metabolic Rate, Adipose Tissue, Ectotherm

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In the fall get fat; look for food. Leptin: a hormone produced by fat cells; signals the brain that we are full. Through the process of glycolysis the fatty acid components are removed from the glycerol, hibernators increase the levels of fatty acids floating in the blood. This leads to the formation of plaque in the arterioles increasing high blood pressure: this plaque formation does not occur in bears. Polyunsaturated fatty acids (pufa), omega 3 and omega 6 fatty acids: enter hibernation state; hibernation is triggered by hp. Hp is produced in the liver, exported in the blood and taken up in the brain. The theory is that hp is somehow modified in the brain before hibernation. This modification is believed to serve as a trigger for the animal to go into hibernation. Normally atp supply and atp demand are in equilibrium with each other. Small animals are reducing metabolic rate by ~80%; below basal metabolic rate.

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