CHEM 2OA3 Lecture Notes - Chch-Dt, Alkoxide, Deprotonation

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Cyclohexane with an mgx connected to one carbon + (h)(ch3)>c=o ---a . Learn what an lda is in an e2 reaction!!!!! Practice a bunch of these retrosynthetic analysis problems, and learn all the reaction types!!!!! R-o-h + base ro- (alkoxide) + h:base: want to use a really strong base to make an alkoxide, ch3oh + n-(two ch3-ch-ch3 branches on it)li+ ch3o-li+ + n(two ch3- Ch3ch2oh + ch3ch2ch2ch2-li ch3ch2o-li+ + ch3ch2ch2ch3 (pka ~50) Ch3ch2oh + k+-h- ch3ch2o-k+ + h2 (pka ~40) 2 h-o-h + 2 na 2 na+o-h + h2. 2 ch3oh + 2 na 2 na+o-ch3 + h2. R-o-h + h+ ro+h2 (alkyloxonium ion: if you can make something that has a part of it looking like a stable thing (in this case water), it is a really good leaving group. C(ch3)3(oh) ---hbr c(ch3)3br + alkene from e1 reaction: c(ch3)3(oh) c(ch3)3(o+