HTHSCI 1CC6 Lecture Notes - Lecture 17: Tubular Fluid, Basal Lamina, Collecting Duct System

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These all occur because cell is semi permeable and water moves to correct osmotic disequilibrium: role of fluid intake and output in fluid balance, electrolyte composition, neural control. Homeostasis of body fluid volume depends in large part on the ability of the kidneys to regulate the rate of water loss in urine. Normally functioning kidneys produce a large volume of dilute urine when fluid intake is high, and a small volume of concentrated urine when fluid intake is low or fluid loss is large. Thirst mechanism - negative feedback controlled by hypothalamus. Tubular secretion: selective adding to waste from the blood occurs along tubule and collecting duct. Filtration: passive if it fits through the slits it will go through fenestrations mostly only stop. Rbcs: nonselective, lg. surface area, mesangial cells, thin and porous, bp glomerular pressure is pretty high in comparison to other locales, colloid osmotic and oncotic pressures, anti-diuretic hormone (adh): everything.

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