HTHSCI 1DT3 Lecture Notes - Lecture 9: Endosome, Elisa, Macrophage
Document Summary
Mod. 3-17 the pathogenesis of a flu pandemic 1. Demonstrate characteristic pandemic strain" illness: southern california. Share genetic elements between flu virus (all flu a) Had classical swine from 1918, north ameriva avian and the common human. It had inherent adamantane resistance but inherent oseltamivir (most common antiviral drug) sensitivty: met definition, yes to first two, mexican wave. In pandemic, more young people: 16-44 were infected, seasonal are those in people with udnerlying health problems like asthmatics or elderly. Obese people, pregnant women, immuno-compromised (like chemotherapy or those udnergoing transplant: symptoms, clinicl diagnosis si difficult as need fever and two or more symptoms, sob need to sick medical attention, lymphopsrniai is cmmon and ck increase. Mod. 3-17 the pathogenesis of a flu pandemic 2. Type 1 respiratory failure: radiology, get some flufy lung field, but by day 14, get resolution of nasty process, alveolar macrophages, bacterial pneumonia, non-infectious complications. Process of fibrosis: h1n1, highly level in severely ill.