HTHSCI 1DT3 Lecture Notes - Lecture 5: Eosinophilia, Methacholine, T Helper Cell
13 Aug 2020
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Mod. 1-21 proof of concept clinical studies with new drugs for asthma and copd 2. Mod. 1-21 proof of concept clinical studies with new drugs for asthma and copd 3. Conclusion: results with mabs in asthma have been disappointing, asthma is a heterogeneous disease and mabs must be targeted to the right patients, new theory that asthma could be a microbial disease of innate immunity, summary. Their pamps stimulate the prr causing a highly stimulated innate immune system: anti-ige (iv/sc) works well on iac and decreases ear and lar. Much more precise and can pick up changes. Mod. 1-21 proof of concept clinical studies with new drugs for copd. Immunology involves the innate inflammatory response to oxidants and microbes: pharmacologically insensitive to steroid and difficult to reverse mucus hypersecretion, small airway fibrosis and lung destruction, clinically, there are heterogeneity of pulmonary and systemic features. In industrialised western countries, mainly affect the smokers (1 billion smokers)
