HTHSCI 1DT3 Lecture Notes - Lecture 4: Song Min-Ho, Elastase, Enzyme

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Mod. 1-5 non-invasive markers of airway inflammation 2. Ting joe li yah: marked flow dependency of no, notes, studies. Need the same expiration flow rate for reproducibility and to compare results. Blow against resistance to isolate nasal cavity contamination. Constant flow because no is flow rate dependent. Asthma: high bronchial no and low alveoli no. Copd: high alveoli no and low bronchial no: conclusion for no, exhale no is simple, reproducible, online, repeatable and useful in severe asthma, especially in children. No develop asthma attack: exhale no maybe useful: Expensive and cumbersome (can use mino, which is accurate and cheaper) Mod. 1-5 non-invasive markers of airway inflammation 3. Contradictory reports on the reproducibility of eia measurements: ph, reduced due to inflammation: independent groups confirmed the level of validation. Best mode of standardisation still under investigation: ebc comes from anywhere between the condenser and the alveoli. Breathe in and out of same machine, not sterilised. Mod. 1-5 non-invasive markers of airway inflammation 4.

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