HTHSCI 1DT3 Lecture 3: anatomy sur-72-79
26 Dec 2020
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Arise from hair follicle infundibulum: trichilemmal cyst / wen. Cystic swelling related to a synovial lined structures: joint, tendon. Large ulcerating trichilemmal cyst on the scalp. Cystic protrusion from synovial cavity of arthritic joint. Benign nerve sheath tumour arising from schwann cells. Overgrowth of all layers of the skin c a central vascular core. Developmental inclusion of epidermis along lines of skin fusion. Most commonly on hands, face, gums and lips. Mostly on the lower limbs of young to middle-aged women. Surgical excision only indicated if malignant growth suspected. Uk incidence = 10 000/yr and 2000 deaths/yr. Sunlight: esp. intense exposure in early years. Grow slowly, metastasise late = better prognosis. Invade deeply and metastasis early = poor prog. Thickness of tumour to deepest point of dermal invasion. Excision + 2o margin excision depending on bres depth. Adjuvant chemo (may use isolated limb perfusion) Male sex (more tumours on trunk cf. females) Ulcerated lesion c hard, raised everted edges.
