HTHSCI 1DT3 Lecture Notes - Lecture 11: Phyllodes Tumor, Benign Tumor, Mammography

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 1DT3
• Professor: Carl Richards

Document Summary

Ca @ 1%/yr (10x risk) in ipsilateral breast. Risk ca risk (x10) in both breasts. Extensive or multifocal mastectomy + reconstruction + snb. Bilateral prophylactic mastectomy or close watching c mammographic screening. Chronic limb ischaemia: presentation and classification 86. Chronic limb ischaemia: investigation and management 87. 5% of males >50yrs have intermittent claudication. Persistent rest pain requiring analgesia for 2wks. Typically asymptomatic until 50% stenosis (vasculitis and fibromuscular dysplasia are v. rare causes) Atherosclerosis summary: endothelial injury: haemodynamic, htn, lipids, chronic inflammation. Lymphocyte and smc recruitment: sm proliferation: conversion of fatty streak to atherosclerotic plaque. Atherosclerosis = arterial hardening specifically due to atheroma. Necrotic centre: cell debris, cholesterol, ca, foam cells. Cramping pain after walking a fixed distance. Calf pain = superficial femoral disease (commonest) Buttock pain = iliac disease (internal or common) Due to co and loss of gravity help. Atherosclerotic occlusion of abdominal aorta and iliacs.