HTHSCI 1DT3 Lecture Notes - Lecture 3: Acute Limb Ischaemia, Endarterectomy, Aortitis

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Stroke: sudden neurological deficit of vascular origin lasting >24h. Tia: sudden neurological deficit of vascular origin lasting <24h (usually lasts <1h) c complete recovery. Turbulent flow shear stress @ carotid bifurcation promoting atherosclerosis and plaque formation. Plaque rupture complete occlusion or distal emboli. Less invasive: hospital stay, infection, cn injury. There is concern over stroke risk, esp. pts. Meta-analysis shows no sig difference in mortality vs. Younger pts. have best risk / benefit ratio. Abnormal dilatation of a blood vessel > 50% of its normal diameter. Dilatation of a blood vessel involving all layers of the wall and is >50% of its normal diameter. Collection of blood around a vessel wall that communicates c the vessel lumen. Vessel dilatation caused by blood splaying apart the media to form a channel w/i the vessel wall. 50% of pts. c popliteal aneurysm also have aaa. Thrombosis and distal embolism is main complication. Stable: elective grafting + tie off vessel.

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