HTHSCI 1DT3 Lecture Notes - Lecture 1: Intramuscular Injection, Tumor Necrosis Factor Alpha, Ontogeny

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Document Summary

Antigens usually very complex chemical composition of epitones. Innate immune responses can"t tell difference between different bacteria; natural killer cells to battle cancer. Interactions due to receptors between molecules, calls, cell surface receptors. T cells and subsets: master control cell of adaptive immune system. Resting helper t cell in blood, sytocines = t helper cells. T killer cells after activated are effector cells, e. g kill virus infected or tumour cell, release enzymes that kill cell, can be activated to a higher degree than nk cells. T cells contact dendritic cells (presents antigen) as well as b cells (present antigen to t cell) T cell receptors all the same recognize one epitope. Killer cells cytotoxic ts and nks; causes death after contact, one example grenzime injection. Including b cell receptors (antibody) have receptor, antibody, has specific specificity (detects on epitope), many different b cells that have different specificities on surface. Antigen receptors: b cell, killer cell, helper t cell.

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