HTHSCI 1H06 Lecture Notes - Lecture 7: Adrenergic Receptor, Peripheral Nervous System, Central Nervous System

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Sympathetic: flight, fight, freight: parasympathetic: rest, relaxation, rumination. Somatic motor division: control of striated muscles, voluntary muscles, parasympathetic vs sympathetic, parasympathetic: long pre-ganglion short post-ganglion, acetlycholine use on effector, receptors are muscarinic ach receptors, ganglia close to their effectors. Sympathetic: short pre-ganglion, long post-ganglion, norepinephrine used on effector, adrenergic receptors. Input is thoraco-lumbar: ganglia far from effectors, ans control (equal sns / pns; one predominates; or exclusive innervation) provide examples. Sludd (cid:894)or the three r"s(cid:895); the three f"s: rest, relaxation, rumination, or, or, urination. Fright: digestion, defecation, the mighty vagus nerve. If vagusly dominant, digestion is fast, heart rate is slow, low blood pressure: autonomic receptors, cholinergic (muscarinic vs nicotinic, found in synapse of sympathetic and parasympathetic ganglia, and postganglionic parasympathetic effectors, muscarinic: found on all parasympathetic target organs. Leads to decreases heart rate, increased intestinal motility and all parasympathetic effects: nicotinic: found in sympathetic and parasympathetic ganglia. Stimulation leads to relatively long term activation of neurons.

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