HTHSCI 1H06 Lecture 27: 27- Adrenal Glands and Disorders

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Hormones made by outer cortex are all lipophilic so it uses fat as a backbone to create these hormones. Outer adrenal cortex, divided into 3 zones (gfr) Sympathetic function, release of e and ne directly into bloodstream. Catecholamines also dump into blood to augment sympathetic response. Alters serum na+ and k+ balance, helps maintain high sodium concentration outside cell and high potassium inside cell. Water is retained in blood due to high na+ Stimulates juxtaglomerular cells of kidneys after detecting stimulus. Converted to angiotensin i by renin to help develop and maintain bp. Angiotensin i converted by angiotensin-converting enzyme (ace) in lungs to angiotensin ii. Blood pressure increases until it returns to normal and inhibits step 4 via negative feedback. In kidneys, increased na+ and water resorption and increased secretion of k+ and h+ into urine via nephrons. Substrates go to liver and make new glucose to allow cns and.

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